Acetaminophen Toxicity Update (N-Acetylcysteine-NAC)
Documents are being circulated to Southern Health-Santé Sud (SH-SS) clinical teams to prepare for the April 1, 2026 go-live for the Provincial Treatment of Acetaminophen Toxicity in alignment with the Ontario Poison Centre change.
- Shared Health Memo-Acetaminophen Toxicity Update (N-Acetylcysteine-NAC) March 20
- Acetaminophen Toxic Ingestion Provincial Standard March 17 (new)
The following provincial clinical documents will be active in SH-SS starting April 1 at 10:30am, at the same time the SH-SS BBraun Infusomat acetylcysteine drug library update occurs. DO NOT remove old paper documents and replace with the new ones until then. Documents will be available for printing on the Shared Health Document Library – Provincial Documents site on April 1. The current SH-SS Acetaminophen Overdose Treatment Standard Orders will be archived and links to new provincial clinical documents will be added on SH-SS StaffNET Policies & Forms for future access.
- Provincial NAC Order Set March 20
- Supplementary Resource Acetaminophen Toxic Ingestion March 20
- Provincial CPG Acetaminophen Toxic Ingestion March 20
SH-SS specific direction and resources to support new protocol:
- SH-SS Memo-Large Volume Infusion Pump Infusomat-Drug Library Update Acetylcysteine April 2026
- SH-SS Parenteral Drug Monographs below and will be available on StaffNET for printing on April 1st.
- SH-SS Acetaminophen Toxicity information session poster March 27
- SH-SS Staff Development encourages staff to attend the Ontario Poison Control training sessions (details in Shared Health March 20, 2026 memo). Site Educators will connect with staff and use additional resources to support learning and track education. Attached education resources are available for sites to use:
- Drug Library Update reports will be distributed to sites/programs as part of the tracking and validation to confirm updates occur in all pumps.
Staff are encouraged to direct any questions and concerns to their manager/supervisor.
Submitted by: Tamara Burnham, Collaborative Practice Lead