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TO: Physician, Nursing and Pharmacy Staff

hydrALAZINE 20 mg/ mL (1 mL) injection supply from the sole manufacturer is on back order; inventory will deplete prior to its return without conservation.

Effective immediately, restrict the use of hydrALAZINE injection for use in patients when there are no other therapeutic alternatives or when other alternatives have not been effective.

  • Oral hydrALAZINE is freely available and should be used in all situations when the patient can tolerate the oral route.
  • Potential formulary alternatives to hydrALAZINE injection that should be considered, if clinically appropriate for the patient and oral hydralazine is not an option, include:
    • Sublingual alternatives: captopril or clonidine (regular tablets will disperse within 1 minute in mouth – contact pharmacy for more information); nitroglycerin sublingual spray or tablets
    • Parenteral alternatives: labetalol, esmolol, or enalaprilat. In critical care, IV hydrALAZINE should only be used when other parenteral alternatives are contraindicated or when other alternatives have not been effective.

Should hydrALAZINE stock become depleted, each pharmacy department will circulate site specific communication.

Thank you for your support of the ongoing efforts to manage drug supply issues.

Submitte by: Regional Pharmacy
For more info. contact: your site pharmacy or Rizwan Ahmed or Libby Gair

Healthier people. Healthier communities. Thriving together.
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