IV DRUG MANUAL REVISIONS
Please be advised the following monographs have been updated on the Drug Monographs page. For IV Parenteral Drug Manual holders, please add/replace/discard as indicated.
REPLACE ADULT Monograph:
Discard the old monograph, PRINT (using the hyperlink) & replace with the new monograph in the Adult Parenteral Drug Monograph Manual as listed below:
Medication/Topic | Approved Changes |
ampicillin | Reconstitution: Added 1g vials of Auro and Eugia brands NOT MINI BAG PLUS compatible |
caspofungin | Available as: Added CANCIDAS (Merck brand) and Juno brand, Fresenius Kabi brand: Store at room temperature. Reconstitution: Added Table IV Intermittenet: Added Table Max/Single Daily Dose increased to 150mg |
DAPTOmycin | Added: Juno Brand |
desmopression | Added: Cushings Diagnostic Test, hyponatremia Compatability: Added Unknown compatibility with Ringer’s lactate and D5W |
dextrose | IV Infusion: Changed 500mL to 400mL D50W |
DOPamine | Soft Low Dose Limit: Decreased to 0.5mcg IV Infusion: Added Increase by 1 to 5 mcg/kg/min every 10 minutes |
enoxaparin | Other Names: Added Redesca Available As: Added 150mg PFS Dosage: Under Non STEMI/unstable angina patients (regardless of age), maximum dose increased to 150 mg and added Exact dosage will depend if using multi dose vial or pre-filled syringes, and if the CrCl is less than 30 mL/min give daily, Under STEMI (with te-necteplase) patients less than 75 years old: Added dose banding table. Pulmonary Embo-lism (PERT protocol) Maximum single subcutaneous dose 150 mg Additional Notes: Updated |
EPINEPHrine | Dosage: Hypotension refractory to dopamine/dobutamine: Added Increase by doubling the dose (or by 0.02 mcg/kg/min) every 3 to 15 minutes until desired effect Bradycardia: Added Initial 2 to 10 mcg/minute. Usual range 8 to 40 mcg/minute |
esmolol | Additional Notes: Limited data for use beyond 24 hours |
fentaNYL | Compatability: Added Ringers Lactate |
Ferric Derisomaltose | Generic Name changed from iron isomaltoside to Ferric Derisomaltose Dosage: Updated Table |
flumazenil | Added: Contact the Manitoba/Ontario Poison Control Centre at 1-855-776-4766 |
fondaparinux | New Monograph |
fosphenytoin | Dosage: Added mg |
furosemide | Administration Policy: Added IM Injection IV Infusion changed 20mg/hour to 40 mg/hour IV bolus maxium changed from 20mg/minute to 40mg/minute |
gentamicin | IV Intermittent: Dose changed 100mL to 100mg |
glucagon | Dosage: Removed beta blocker or calcium channel blocker overdose and anaphylaxis sections |
inFLIXimab | IV Intermittent: Added 0.2 micron filter |
ketamine LOW | Dosage: IV bolus/IV intermittent changed 0.6mg/kg to 0.5mg/kg Dosage: IV infusion changed 0.15mg/kg/hour to 0.25mg/kg/hour |
metoprolol | Dosage: Updated Acute treatment of arrhythmias section |
pantoprozole | IV intermittent: Added JAMP brand NOT MINI BAG PLUS compatible |
piperacillin-tazobactam | Reconstitution Dilution Administration: Added 4.5 g vials of Auro and Eugia brands are NOT MINI BAG PLUS compatible |
protamine sulfate | Dosage: Added maximum of 50mg protamine per dose |
SUFentanil | IV Infusion: Added non-PVC |
sugammadex | Updated precautions and additional notes |
Submitted by: Cécile Dumesnil, Manager – Pharmacy
For more info. contact: 204-371-5952 or